QS11
Product Specifications
CAS Number
944328-88-5
Target
GTPase|||Others|||Wnt/beta-catenin
Related Pathways
Stem Cells|||Cytoskeletal Signaling|||GPCR/G Protein|||Others
Purity
>99.99%
Bioactivity
QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/?-catenin signaling pathway to upregulate ?-catenin nuclear translocation. Also reduces in vitro migration of metastatic human breast cancer cells.
Smiles
OC[C@H](Cc1ccccc1)Nc1nc(Oc2ccc3CCCc3c2)nc2n(Cc3ccc(cc3)-c3ccccc3)cnc12
Molecular Formula
C36H33N5O2
Molecular Weight
567.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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