PD0325901-O-C2-dioxolane
Product Specifications
CAS Number
2581116-22-3
Target
Ligands for Target Protein for PROTAC, MEK
Related Pathways
PROTAC, MAPK
Bioactivity
The main body of PD0325901-O-C2-dioxolane is PD0325901, which is a typical non-ATP-competitive MEK1/2 (mitogen-activated protein kinase) inhibitor occupying a variant-binding pocket near the ATP-binding site, with anticancer effects of decreasing ERK phosphorylation and inhibiting cell proliferation.
Smiles
O=C(NOCCC1OCCO1)C2=CC=C(F)C(F)=C2NC3=CC=C(I)C=C3F
Molecular Formula
C18H16F3IN2O4
Molecular Weight
508.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
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