EIF4E-IN-1
Product Specifications
CAS Number
2573979-31-2
Target
PERK, Others
Related Pathways
Others, Apoptosis
Bioactivity
EIF4E-IN-1 (WO2021003194A1, compound Y), is a highly effective inhibitor of eIF4E, a key protein involved in immunosuppression. By targeting immune checkpoint proteins such as PD-1, PD-L1, LAG3, TIM3, and IDO, eIF4E-IN-1 functions to disrupt immune suppression and promote immune release in specific diseases such as cancer and infectious diseases.
Smiles
CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O
Molecular Formula
C33H28ClF3N6O4S
Molecular Weight
697.13
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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