PI3Kγ inhibitor 5
Product Specifications
CAS Number
2566569-31-9
Target
Others, PI3K
Related Pathways
Others, PI3K/Akt/mTOR signaling
Bioactivity
PI3Kγ inhibitor 5 is a potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ), exhibiting an exceptional IC50 value of 34 nM.
Smiles
C[C@@H](C1CC1)N1Cc2cc(cc(OC(F)F)c2C1=O)-c1ccn2nc(N)c(C(=O)N[C@H]3CC[C@@](C)(O)CC3)c2n1 |wU:33.36,1.0,wD:30.32,33.37,(10.69,-4.01,;9.15,-4.01,;8.38,-5.34,;8.38,-6.88,;7.05,-6.11,;8.38,-2.67,;6.85,-2.51,;6.53,-1.01,;5.2,-.24,;5.2,1.3,;6.53,2.07,;7.87,1.3,;9.2,2.07,;9.2,3.61,;7.87,4.38,;10.53,4.38,;7.87,-.24,;9.01,-1.27,;10.52,-.95,;3.86,2.07,;3.86,3.61,;2.53,4.38,;1.2,3.61,;-.27,4.09,;-1.17,2.84,;-2.71,2.84,;-.27,1.6,;-.74,.13,;.29,-1.01,;-2.25,-.19,;-2.73,-1.65,;-4.23,-1.97,;-4.71,-3.44,;-3.68,-4.58,;-3.1,-6.01,;-4.98,-5.4,;-2.17,-4.26,;-1.7,-2.8,;1.2,2.07,;2.53,1.3,)|
Molecular Formula
C28H32F2N6O4
Molecular Weight
554.599
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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