Nur77 modulator 1
Product Specifications
CAS Number
2469975-55-9
Target
Apoptosis, NR4A, Others
Related Pathways
Others, Apoptosis, Endocrinology/Hormones
Purity
0.9962
Bioactivity
Nur77 modulator 1 is an effective Nur77 binder (KD = 3.58 μM) that up-regulates Nur77 expression, mediates its sub-cellular localization, induces Nur77-dependent ER stress and autophagy, and leads to cell apoptosis, demonstrating anti-hepatoma activity.
Smiles
COc1cccc2c(Nc3ccc4[nH]c(cc4c3)C(=O)N\N=C\c3ccc(SC)cc3)cc(C)nc12
Molecular Formula
C28H25N5O2S
Molecular Weight
495.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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Myosin Light Chain Kinase, Smooth Muscle, NT (smMLCK, MLCK, MLCK1, MLCK108, MLCK210, MYLK, MYLK1, DKFZp686I10125, FLJ12216, Kinase-related Protein, KRP, MSTP083, Telokin) (APC)
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