S65487 sulfate
Product Specifications
CAS Number
2416937-01-2
Target
Others, Apoptosis, Bcl-2 Family
Related Pathways
Others, Apoptosis
Bioactivity
S65487 (VOB560) sulfate, a potent and selective Bcl-2 inhibitor, demonstrates activity against BCL-2 mutations, including G101V and D103Y, while showing poor affinity for MCL-1, BFL-1, and BCL-XL. It induces apoptosis and possesses anticancer activities.
Smiles
OS(O)(=O)=O.Cc1c(cc(C#N)n1C)N(C(=O)c1cc(-c2cc(Cl)ccc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n(C)c1C)c1ccc(O)cc1
Molecular Formula
C41H43ClN6O8S
Molecular Weight
815.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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