V-9302 hydrochloride
Product Specifications
CAS Number
2416138-42-4
Target
MTOR, ASCT, Autophagy, ROS
Related Pathways
Membrane transporter/Ion channel, Immunology/Inflammation, PI3K/Akt/mTOR signaling, Autophagy
Purity
0.9731
Bioactivity
V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5. V-9302 hydrochloride impedes glutamine uptake mediated by ASCT2 (IC50=9.6 μM), inhibits the mTOR signalling pathway, increases oxidative stress and ROS levels, induces autophagy, and exerts antitumour effects.
Smiles
C(N(CC1=C(OCC2=CC(C)=CC=C2)C=CC=C1)CC[C@@H](C(O)=O)N)C3=C(OCC4=CC(C)=CC=C4)C=CC=C3.Cl
Molecular Formula
C34H39ClN2O4
Molecular Weight
575.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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