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V-9302 hydrochloride

Product Specifications

CAS Number

2416138-42-4

Target

MTOR, ASCT, Autophagy, ROS

Related Pathways

Membrane transporter/Ion channel, Immunology/Inflammation, PI3K/Akt/mTOR signaling, Autophagy

Purity

0.9731

Bioactivity

V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5. V-9302 hydrochloride impedes glutamine uptake mediated by ASCT2 (IC50=9.6 μM), inhibits the mTOR signalling pathway, increases oxidative stress and ROS levels, induces autophagy, and exerts antitumour effects.

Smiles

C(N(CC1=C(OCC2=CC(C)=CC=C2)C=CC=C1)CC[C@@H](C(O)=O)N)C3=C(OCC4=CC(C)=CC=C4)C=CC=C3.Cl

Molecular Formula

C34H39ClN2O4

Molecular Weight

575.14

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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