Nicotinamide riboside malate
Product Specifications
CAS Number
2415659-01-5
Target
Others, Sirtuin, Endogenous Metabolite
Related Pathways
Metabolism, DNA Damage/DNA Repair, Chromatin/Epigenetic, Others
Bioactivity
Nicotinamide riboside malate is an orally active NAD+ precursor that elevates NAD+ levels and stimulates the activity of SIRT1 and SIRT3. Functioning as a vitamin B3 (niacin) source, it augments oxidative metabolism and provides protection against metabolic abnormalities induced by a high-fat diet. Additionally, Nicotinamide riboside malate mitigates cognitive decline in a genetically modified mouse model of Alzheimer's disease.
Smiles
O[C@H](CC([O-])=O)C(O)=O.NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Molecular Formula
C15H20N2O10
Molecular Weight
388.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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