(S) -Indoximod
Product Specifications
CAS Number
21339-55-9
Target
IDO, Indoleamine 2,3-Dioxygenase (IDO)
Related Pathways
Metabolism
Purity
0.9969
Bioactivity
(S) -Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, induction of IDO1 protein expression in tumor of C57BL/6 mouse allografted with mouse LLC cells at 200 mg/kg, antitumor activity against mouse LLC cells allografted in C57BL/6 mouse, antiproliferative activity against mouse LLC cells at 50 uM.
Smiles
Cn1cc(C[C@H](N)C(O)=O)c2ccccc12
Molecular Formula
C12H14N2O2
Molecular Weight
218.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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