Decursin
Product Specifications
CAS Number
5928-25-6
Target
PKC, CXCR, Apoptosis
Related Pathways
Apoptosis, Cytoskeletal Signaling, Immunology/Inflammation, GPCR/G Protein, Autophagy, Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
1. Decursin (Decursinol angelate) is able to attenuate kainic acid-induced seizures and could have potential as an antiepileptic drug. 2. Decursin exhibits hepatoprotective effects , potentially by inhibiting the TGF-β1 induced NOX activation and Smad signaling. 3. Decursin has anti-cancer activity , mediated suppression of the PKCα, MAPK and NF-κB pathways in MCF-7 cells. 4. Decursin exhibits cytotoxicity against various human cancer cells and to possess anti-amnesic activity in vivo through the inhibition of AChE activity.
Smiles
CC(C)=CC(=O)O[C@H]1Cc2cc3ccc(=O)oc3cc2OC1(C)C
Molecular Formula
C19H20O5
Molecular Weight
328.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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