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Aristolactam I

Product Specifications

CAS Number

13395-02-3

Target

Drug Metabolite, Cadherin, Aquaporin, Caspase, Apoptosis, TGF-beta/Smad

Related Pathways

Membrane transporter/Ion channel, Stem Cells, Apoptosis, Cytoskeletal Signaling, Metabolism, Proteases/Proteasome

Purity

0.9963

Bioactivity

1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF-beta1 pathway. 3. Aristololactam I may be one of toxic metabolites in Chinese herbs containing AA which participate in renal damage and fibrosis.

Smiles

COc1cccc2c1cc1NC(=O)c3cc4OCOc4c2c13

Molecular Formula

C17H11NO4

Molecular Weight

293.27

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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