RMC-6272
Product Specifications
CAS Number
2382769-46-0
Target
MTOR, Others
Related Pathways
PI3K/Akt/mTOR signaling, Others
Bioactivity
RMC-6272 (RM-006) is a bi-steric inhibitor that selectively targets mTORC1 with potent inhibition (>10-fold) over mTORC2. Compared to Rapamycin, RMC-6272 shows enhanced inhibition of mTORC1 and induces increased cell death in TSC2 null tumors.
Smiles
[H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(C[C@@H](O)[C@H](C)\C=C(C)\[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)\C=C\C=C\C=C(C)\[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NCCS(=O)(=O)c2ccc(C(=O)N3CCOc4ccc(cc4C3)-c3ccc(N)nc3)c(C)c2F)[C@@H](C1)OC
Molecular Formula
C95H141FN6O27S
Molecular Weight
1850.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
OARA04113-500UL 500 µL
Rat IgG (H&L) Antibody F (ab') 2 - Texas Red Conjugated
Sign In for Pricing
View Details 
127283-ML405 100 µL
GGA1 (ADP-ribosylation Factor-binding Protein GGA1, Gamma-adaptin-related Protein 1, Golgi-localized, gamma Ear-containing, ARF-binding Protein 1) (MaxLight 405) discontinued
Sign In for Pricing
View Details