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RMC-6272

Product Specifications

CAS Number

2382769-46-0

Target

MTOR|||Others

Related Pathways

PI3K/Akt/mTOR signaling|||Others

Bioactivity

RMC-6272 (RM-006) is a bi-steric inhibitor that selectively targets mTORC1 with potent inhibition (>10-fold) over mTORC2. Compared to Rapamycin, RMC-6272 shows enhanced inhibition of mTORC1 and induces increased cell death in TSC2 null tumors.

Smiles

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