(32-Carbonyl) -RMC-5552

Product Specifications

CAS Number

2382768-55-8

Target

MTOR|||Others

Related Pathways

PI3K/Akt/mTOR signaling|||Others

Bioactivity

(32-Carbonyl) -RMC-5552 is a highly effective mTOR inhibitor, inhibiting both mTORC1 and mTORC2 substrate phosphorylation. It significantly suppresses the phosphorylation of p-P70S6K- (T389), p-4E-BP1- (T37/36), and p-AKT1/2/3- (S473) with pIC50 values >9, >9, and 8~9, respectively.

Smiles

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