CDK4/6-IN-5
Product Specifications
CAS Number
2380321-50-4
Target
Others|||CDK
Related Pathways
Cell Cycle/Checkpoint|||Others
Bioactivity
CDK4/6-IN-5 is a highly effective inhibitor of CDK4 and CDK6, with Ki values of 0.2 nM for CDK4/Cyclin D1 and 4.4 nM for CDK6/Cyclin D3 (WO2019207463A1, example A93) .
Smiles
C[C@@H](O)c1nc2c(F)cc(cc2n1C(C)C)-c1nc(N[C@@H]2CCN(C[C@H]2O)S(C)(=O)=O)ncc1Cl
Molecular Formula
C22H28ClFN6O4S
Molecular Weight
527.01
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Curated Selection
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