AU-15330
Product Specifications
CAS Number
2380274-50-8
Target
PROTACs, Epigenetic Reader Domain
Related Pathways
PROTAC, Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
AU-15330 is a proteolytic targeting chimera (PROTAC) that simultaneously targets SMARCA4, SMARCA2, and PBRM1 for degradation and exhibits cytotoxicity in H3.3K27M cells but not in H3 wild-type cells. [2]
Smiles
C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CN1CCN(CC1)c1cc(nnc1N)-c1ccccc1O)C(C)(C)C)c1ccc(cc1)-c1scnc1C
Molecular Formula
C39H49N9O5S
Molecular Weight
755.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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