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M-1211

Product Specifications

CAS Number

2377337-93-2

Target

Others|||Epigenetic Reader Domain

Related Pathways

Chromatin/Epigenetic|||Others

Bioactivity

M 1121 is a covalent and orally active inhibitor of the menin-MLL interaction capable of achieving complete and persistent tumor regression.

Smiles

[H][C@]12CN([C@]([H])(CN1C(=O)C=C)C2)S(=O)(=O)c1ccc(cc1)N1CC(CN2CCC(CC2)[C@@](CN2CCC2)(c2cccc(F)c2)[C@@]2([H])CCC[C@@H]2NC(=O)OC)(C1)OC|@@:29,TLB:13:3:12:7.6,THB:8:7:12:3.2|

Molecular Formula

C42H57FN6O6S

Molecular Weight

793.01

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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