Bexotegrast
Product Specifications
CAS Number
2376257-44-0
Target
Integrin
Related Pathways
Cytoskeletal Signaling
Purity
0.9953
Bioactivity
Bexotegrast (PLN-74809) is an orally active and potent inhibitor of αvβ6 and αvβ1 integrins with antifibrotic effects, inhibiting αvβ6 and αvβ1-induced activation of TGF-β. It is applicable for studies of idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP) .
Smiles
N([C@@H](CCN(CCCCC=1NC=2C(=CC1)CCCN2)CCOC)C(O)=O)C=3C4=C(N=CN3)C=CC=C4
Molecular Formula
C27H36N6O3
Molecular Weight
492.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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