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Bexotegrast

Product Specifications

CAS Number

2376257-44-0

Target

Integrin

Related Pathways

Cytoskeletal Signaling

Purity

0.9953

Bioactivity

Bexotegrast (PLN-74809) is an orally active and potent inhibitor of ?v?6 and ?v?1 integrins with antifibrotic effects, inhibiting ?v?6 and ?v?1-induced activation of TGF-?. It is applicable for studies of idiopathic pulmonary fibrosis (IPF) and non-specific interstitial pneumonia (NSIP) .

Smiles

N([C@@H](CCN(CCCCC=1NC=2C(=CC1)CCCN2)CCOC)C(O)=O)C=3C4=C(N=CN3)C=CC=C4

Molecular Formula

C27H36N6O3

Molecular Weight

492.61

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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