SR-717 free acid
Product Specifications
CAS Number
2375420-34-9
Target
Others, STING
Related Pathways
Immunology/Inflammation, Others
Bioactivity
SR-717 free acid is a stable cGAMP mimetic and non-nucleotide STING agonist, demonstrating antitumor activity with EC50 values of 2.1 μM in ISG-THP1 (WT) and 2.2 μM in ISG-THP1 cGAS KO (cGAS KO) cell lines.
Smiles
OC(=O)c1cc(F)c(F)cc1NC(=O)c1ccc(nn1)-n1ccnc1
Molecular Formula
C15H9F2N5O3
Molecular Weight
345.266
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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