Desmorpholinyl Navitoclax-NH-Me

Product Specifications

CAS Number

2365172-82-1

Target

Bcl-2 Family|||Ligands for Target Protein for PROTAC

Related Pathways

Apoptosis|||PROTAC

Purity

0.9987

Bioactivity

Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].

Smiles

CNCC[C@H](CSc1ccccc1)Nc1ccc(cc1S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC2=C(CCC(C)(C)C2)c2ccc(Cl)cc2)CC1

Molecular Formula

C44H51ClF3N5O5S3

Molecular Weight

918.55

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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