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PROTAC IRAK4 degrader-4

Product Specifications

CAS Number

2360528-45-4

Target

Others|||PROTACs|||IRAK

Related Pathways

PROTAC|||Immunology/Inflammation|||NF-?B|||Others

Bioactivity

PROTAC IRAK4 degrader-4 (US20190192668A1, compound I-127) is a Cereblon-based PROTAC specifically designed to target and degrade interleukin-1 receptor-associated kinase 4 (IRAK4) .

Smiles

NC(=O)c1nn(cc1NC(=O)c1coc(n1)-c1ccnc(NCC(F)(F)F)c1)-c1ccc(cc1)C(=O)NCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12

Molecular Formula

C41H38F3N11O10

Molecular Weight

901.817

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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