PROTAC IRAK4 degrader-4
Product Specifications
CAS Number
2360528-45-4
Target
Others|||PROTACs|||IRAK
Related Pathways
PROTAC|||Immunology/Inflammation|||NF-?B|||Others
Bioactivity
PROTAC IRAK4 degrader-4 (US20190192668A1, compound I-127) is a Cereblon-based PROTAC specifically designed to target and degrade interleukin-1 receptor-associated kinase 4 (IRAK4) .
Smiles
NC(=O)c1nn(cc1NC(=O)c1coc(n1)-c1ccnc(NCC(F)(F)F)c1)-c1ccc(cc1)C(=O)NCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Molecular Formula
C41H38F3N11O10
Molecular Weight
901.817
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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