NVP-BSK805 trihydrochloride
Product Specifications
CAS Number
2320258-95-3
Target
Others, JAK
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Stem Cells, Angiogenesis, Chromatin/Epigenetic, Others
Bioactivity
NVP-BSK805 trihydrochloride is a potent ATP-competitive inhibitor of JAK2, exhibiting IC50 values of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM against JAK2 JH1, JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively.
Smiles
Cl.Cl.Cl.Fc1cc(cc(F)c1CN1CCOCC1)-c1cccc2ncc(nc12)-c1cnn(c1)C1CCNCC1
Molecular Formula
C27H31Cl3F2N6O
Molecular Weight
599.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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