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TBK1/IKK?-IN-6

Product Specifications

CAS Number

2306877-20-1

Target

I?B/IKK|||Others

Related Pathways

Others|||NF-?B

Bioactivity

TBK1/IKK?-IN-6 (example 110) is a potent inhibitor of TBK1 and IKK?, exhibiting IC50 values below 100 nM for both enzymes.

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COc1nc(Nc2nccc(n2)-c2ccc(OC3CCN(CC3(F)F)C(=O)[C@@H](C)O)c(c2)C#N)ccc1N1CCN(C)C[C@H]1C

Molecular Formula

C31H36F2N8O4

Molecular Weight

622.678

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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