TBK1/IKK?-IN-6

2306877-20-1

I?B/IKK|||Others

Others|||NF-?B

TBK1/IKK?-IN-6 (example 110) is a potent inhibitor of TBK1 and IKK?, exhibiting IC50 values below 100 nM for both enzymes.

COc1nc(Nc2nccc(n2)-c2ccc(OC3CCN(CC3(F)F)C(=O)[C@@H](C)O)c(c2)C#N)ccc1N1CCN(C)C[C@H]1C

C31H36F2N8O4

622.678

Cool pack

-20°C