PROTAC ERRα Degrader-3
Product Specifications
CAS Number
2306388-65-6
Target
Estrogen Receptor/ERR, PROTACs
Related Pathways
Endocrinology/Hormones, PROTAC
Bioactivity
PROTAC ERRα Degrader-3 is a highly effective and selective von Hippel-Lindau-based ligand that efficiently degrades the ERRα protein, reducing its levels by >80% at a concentration of 30 nM. Notably, this compound shows no activity against the ERRβ and ERRγ proteins.
Smiles
COc1cc(\C=C(/C#N)C(=O)NCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F
Molecular Formula
C47H50F6N6O7S
Molecular Weight
957
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6274836-01 0.1 mL
ARHGAP1, ID (ARHGAP1, CDC42GAP, RHOGAP1, Rho GTPase-activating protein 1, CDC42 GTPase-activating protein, GTPase-activating protein rhoOGAP, Rho-related small GTPase protein activator, Rho-type GTPase-activating protein 1, p50-RhoGAP) (MaxLight 490)
Sign In for Pricing
View Details MBS6274836-02 5x 0.1 mL
ARHGAP1, ID (ARHGAP1, CDC42GAP, RHOGAP1, Rho GTPase-activating protein 1, CDC42 GTPase-activating protein, GTPase-activating protein rhoOGAP, Rho-related small GTPase protein activator, Rho-type GTPase-activating protein 1, p50-RhoGAP) (MaxLight 490)
Sign In for Pricing
View Details 
MBS1269972-01 0.01 mg Plasmid + 0.2 mL Glycerol-Stock
HLA-B cDNA Clone
Sign In for Pricing
View Details MBS1269972-02 5x 0.01 mg Plasmid + 5x 0.2 mL Glycerol-Stock
HLA-B cDNA Clone
Sign In for Pricing
View Details 
43739111 3x 1.0 µg
SIAE sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details