PROTAC ERR? Degrader-3
Product Specifications
CAS Number
2306388-65-6
Target
Estrogen Receptor/ERR|||PROTACs
Related Pathways
Endocrinology/Hormones|||PROTAC
Bioactivity
PROTAC ERR? Degrader-3 is a highly effective and selective von Hippel-Lindau-based ligand that efficiently degrades the ERR? protein, reducing its levels by >80% at a concentration of 30 nM. Notably, this compound shows no activity against the ERR? and ERR? proteins.
Smiles
COc1cc(\C=C(/C#N)C(=O)NCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F
Molecular Formula
C47H50F6N6O7S
Molecular Weight
957
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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