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PROTAC ERR? Degrader-3

Product Specifications

CAS Number

2306388-65-6

Target

Estrogen Receptor/ERR|||PROTACs

Related Pathways

Endocrinology/Hormones|||PROTAC

Bioactivity

PROTAC ERR? Degrader-3 is a highly effective and selective von Hippel-Lindau-based ligand that efficiently degrades the ERR? protein, reducing its levels by >80% at a concentration of 30 nM. Notably, this compound shows no activity against the ERR? and ERR? proteins.

Smiles

COc1cc(\C=C(/C#N)C(=O)NCCCCC(=O)N[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)NCc2ccc(cc2)-c2scnc2C)C(C)(C)C)ccc1OCc1ccc(cc1C(F)(F)F)C(F)(F)F

Molecular Formula

C47H50F6N6O7S

Molecular Weight

957

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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