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DMNPE-4 AM-caged-calcium

Product Specifications

CAS Number

2253744-58-8

Target

Others, Calcium Channel

Related Pathways

Metabolism, Others, Membrane transporter/Ion channel

Bioactivity

DMNPE-4 AM-caged-calcium, a photolabile analogue of EGTA, is a highly efficient Ca2+-selective cage. At pH 7.2 and pH 7.4, its Kd for Ca2+ is measured at 48 nM and 19 nM, respectively. Upon photolysis, DMNPE-4 AM-caged-calcium exhibits a decreased affinity for Ca2+ (~2 nM Kd) .

Smiles

COc1cc(C(CN(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)OCCOCCN(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)c(cc1OC)N(=O)=O

Molecular Formula

C34H47N3O22

Molecular Weight

849.749

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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