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Lifitegrast sodium

Product Specifications

CAS Number

1119276-80-0

Target

Integrin

Related Pathways

Cytoskeletal Signaling

Purity

0.9933

Bioactivity

Lifitegrast sodium (SAR-1118-023 sodium) is a small molecule integrin antagonist that inhibits T cell-mediated inflammation by blocking the binding of two important cell surface proteins (lymphocyte function-associated antigen 1 and intercellular adhesion molecule 1), which reduces inflammation of the ocular surface, and may be used in the study of dry eye.

Smiles

ClC1=C2C(CN(CC2)C(C3=CC=C(C=CO4)C4=C3)=O)=CC(Cl)=C1C(N[C@H](C([O-])=O)CC5=CC(S(C)(=O)=O)=CC=C5)=O.[Na+]

Molecular Formula

C29H23Cl2N2NaO7S

Molecular Weight

637.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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