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RMC-4529

Product Specifications

CAS Number

2250059-27-7

Target

MTOR, Others

Related Pathways

Others, PI3K/Akt/mTOR signaling

Bioactivity

RMC-4529 is a chemical compound that demonstrates potent inhibition, with an IC50 value of 1.0 nM, against p-4E-BP1- (T37/46) in mTOR kinase cellular assays.

Smiles

[H][C@@]12CC[C@@H](C)[C@@](O)(O1)C(=O)C(=O)N1CCCC[C@@]1([H])C(=O)O[C@@]([H])(C[C@@H](OC)[C@H](C)\C=C(C)/[C@@H](O)[C@@H](OC)C(=NOCc1cn(CCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NCCCCn3nc(-c4ccc5oc(N)nc5c4)c4c(N)ncnc34)nn1)[C@H](C)C[C@H](C)\C=C/C=C\C=C(C)/[C@H](C2)OC)[C@H](C)C[C@@H]1CC[C@@H](O)[C@@H](C1)OC |w:40.42,c:113,115,t:33,117|

Molecular Formula

C90H139N13O23

Molecular Weight

1771.17

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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