BAY-6672
Product Specifications
CAS Number
2247517-53-7
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein, Immunology/Inflammation
Purity
0.9951
Bioactivity
BAY-6672 is a selective human prostaglandin F (FP) receptor antagonist that is highly potent (IC50=11 nM), orally available and well permeable. It exerts antifibrotic effects by inhibiting prostaglandin F2α (PGF2α) activity through antagonizing the FP receptor, and has in vivo efficacy in animal models of idiopathic pulmonary fibrosis (IPF) .
Smiles
C(NC[C@H](CCC(O)=O)C1=C(Cl)C=CC=C1)(=O)C=2C3=C(N=C(C2C)N4CCCC4)C=CC(Br)=C3
Molecular Formula
C26H27BrClN3O3
Molecular Weight
544.87
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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