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BAY-6672

Product Specifications

CAS Number

2247517-53-7

Target

Prostaglandin Receptor

Related Pathways

GPCR/G Protein|||Immunology/Inflammation

Purity

0.9951

Bioactivity

BAY-6672 is a selective human prostaglandin F (FP) receptor antagonist that is highly potent (IC50=11 nM), orally available and well permeable. It exerts antifibrotic effects by inhibiting prostaglandin F2? (PGF??) activity through antagonizing the FP receptor, and has in vivo efficacy in animal models of idiopathic pulmonary fibrosis (IPF) .

Smiles

C(NC[C@H](CCC(O)=O)C1=C(Cl)C=CC=C1)(=O)C=2C3=C(N=C(C2C)N4CCCC4)C=CC(Br)=C3

Molecular Formula

C26H27BrClN3O3

Molecular Weight

544.87

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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