VGSC blocker-1
Product Specifications
CAS Number
2230472-55-4
Target
Others|||Sodium Channel
Related Pathways
Others|||Membrane transporter/Ion channel
Bioactivity
VGSC blocker-1 is a powerful small molecule that serves as a blocker for the neonatal isoform of the VGSC subtype known as Nav1.5 (nNav1.5) . It effectively blocks INa peak currents by 34.9% at a concentration of 1 ?M, and demonstrates a 0.3% inhibition of cell invasion at the same concentration in the MDA-MB-231 human breast cancer cell line, without compromising cell viability.
Smiles
Fc1ccc(cc1)C(CCCNCCCN1CCCCC1)c1ccc(F)cc1
Molecular Formula
C24H32F2N2
Molecular Weight
386.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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