Crelosidenib
Product Specifications
CAS Number
2230263-60-0
Target
Isocitrate Dehydrogenase (IDH) |||Dehydrogenase
Related Pathways
Metabolism
Purity
0.9854
Bioactivity
Crelosidenib is a potent and selective mutant IDH inhibitor with IC50s of 6.27 nM, 3.71 nM, 36.9 nM, and 11.5 nM for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutases, respectively, and low inhibitory activity against the wild-type IDH enzyme.
Smiles
[C@H](CC1CC1)(C2=CC=C([C@@H](NC=3N=C4C(=CN3)COC(=O)N4CC)C)C=C2)N5CCN(C(C=C)=O)CC5
Molecular Formula
C28H36N6O3
Molecular Weight
504.62
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
EK345270 96 Well
Porcine IGFBP-3 (Insulin Like Growth Factor Binding Protein 3) ValidElisa Kit
Ask
View Details 
MBS2088697-02 5x 96 Tests + MBS2089471 (Support Pack 1,5x 96 Tests)
Human Adiponectin (ADP) ELISA Kit DIY Materials
Ask
View Details 
MBS2088697-04 10x 96 Tests + MBS2089471 (Support Pack 1, 10x 96 Tests)
Human Adiponectin (ADP) ELISA Kit DIY Materials
Ask
View Details ![TAF1B Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1A8]](https://cdn.genprice.uk/products/937/6868c3f3994c49e6dc40229e/imageurl/ta808689bm.webp)
TA808689BM 100 µL
TAF1B Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1A8]
Ask
View Details