ARD-2128
Product Specifications
CAS Number
2222111-87-5
Target
PROTACs, Androgen Receptor
Related Pathways
PROTAC, Endocrinology/Hormones
Purity
0.9972
Bioactivity
ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) that degrades the androgen receptor (AR), effectively reducing AR protein levels, suppressing AR-regulated gene expression in tumor tissues, and inhibiting tumor growth without evident toxicity. This compound holds promise for prostate cancer research.
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=C(C2)N4CCC(CN5CCN(CC5)C6=CC=C(C(N[C@@H]7C(C)(C)[C@@H](OC8=CC(Cl)=C(C#N)C=C8)C7(C)C)=O)C=C6)CC4
Molecular Formula
C45H50ClN7O6
Molecular Weight
820.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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