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GluN2B receptor modulator-1

Product Specifications

CAS Number

2222010-71-9

Target

NMDAR, iGluR

Related Pathways

Membrane transporter/Ion channel, Neuroscience

Purity

0.9956

Bioactivity

GluN2B receptor modulator-1 is a potent and selective allosteric negative modulator of the GluN2B subunit of NMDA receptors, exhibiting an IC50 value of 31 nM, enabling spcific modulation of subunit-specific allosteric control over the transmembrane ion channel pores of the NMDARs. providing a valuable tool in neuropharmacology and receptor-specific mechanisms relevant in the study of neurological diseases.

Smiles

O=C1N(C=2N=CC(=CC2N1CC(=O)N3CCC3)C=4SC(=CC4)C(F)(F)F)C

Molecular Formula

C17H15F3N4O2S

Molecular Weight

396.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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