GluN2B receptor modulator-1
Product Specifications
CAS Number
2222010-71-9
Target
NMDAR, iGluR
Related Pathways
Membrane transporter/Ion channel, Neuroscience
Purity
0.9956
Bioactivity
GluN2B receptor modulator-1 is a potent and selective allosteric negative modulator of the GluN2B subunit of NMDA receptors, exhibiting an IC50 value of 31 nM, enabling spcific modulation of subunit-specific allosteric control over the transmembrane ion channel pores of the NMDARs. providing a valuable tool in neuropharmacology and receptor-specific mechanisms relevant in the study of neurological diseases.
Smiles
O=C1N(C=2N=CC(=CC2N1CC(=O)N3CCC3)C=4SC(=CC4)C(F)(F)F)C
Molecular Formula
C17H15F3N4O2S
Molecular Weight
396.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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