Elomotecan hydrochloride
Product Specifications
CAS Number
220997-99-9
Target
Others, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Others
Bioactivity
Elomotecan hydrochloride (BN 80927), a camptothecin analog from the homocamptothecin family (hCPT), is a highly potent inhibitor of both topoisomerases I and II. It demonstrates superior efficacy in reducing the proliferation of various tumor cells compared to other reference anticancer drugs targeting these topoisomerases.
Smiles
Cl.CC[C@@]1(O)CC(=O)OCc2c1cc1-c3nc4cc(Cl)c(C)cc4c(CN4CCC(C)CC4)c3Cn1c2=O
Molecular Formula
C29H33Cl2N3O4
Molecular Weight
558.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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