Ethaselen
Product Specifications
CAS Number
217798-39-5
Target
Reductase
Related Pathways
Endocrinology/Hormones|||Metabolism
Purity
0.9914
Bioactivity
Ethaselen (BBSKE) is an orally active and selective thioredoxin reductase 1 (TrxR) inhibitor with anticancer activity that directly inhibits TrxR1 activity and is commonly used in combination with oxaliplatin to inhibit tumor growth.Ethaselen induces apoptosis in cancer cells and inhibits the proliferation of colorectal cancer cells.
Smiles
O=C1C=2C=CC=CC2[Se]N1CCN3[Se]C=4C=CC=CC4C3=O
Molecular Formula
C16H12N2O2Se2
Molecular Weight
422.2
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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