CCR4 antagonist 3
Product Specifications
CAS Number
2174938-70-4
Target
CCR|||Others
Related Pathways
GPCR/G Protein|||Immunology/Inflammation|||Others|||Microbiology/Virology
Bioactivity
CCR4 antagonist 3 is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antagonist 3 has antitumor activity.
Smiles
[H][C@@]1(CCCN(CCO)C1)C1CN(C1)c1cnc2c(nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1)C#N
Molecular Formula
C24H27Cl2N7O
Molecular Weight
500.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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