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CCR4 antagonist 3

Product Specifications

CAS Number

2174938-70-4

Target

CCR|||Others

Related Pathways

GPCR/G Protein|||Immunology/Inflammation|||Others|||Microbiology/Virology

Bioactivity

CCR4 antagonist 3 is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antagonist 3 has antitumor activity.

Smiles

[H][C@@]1(CCCN(CCO)C1)C1CN(C1)c1cnc2c(nn([C@H](C)c3ccc(Cl)cc3Cl)c2n1)C#N

Molecular Formula

C24H27Cl2N7O

Molecular Weight

500.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Product Datasheet

https://www.targetmol.com/attachment/DataSheet/AAA7DABF-51B3-4861-B1F5-B1DD3463B4D1/T39661

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