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ε-Amanitin

Product Specifications

CAS Number

21705-02-2

Target

ADC Cytotoxin|||DNA/RNA Synthesis

Related Pathways

DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Antibody-drug Conjugate/ADC Related

Bioactivity

?-Amanitin is a cyclic peptide obtained from various mushroom species. It exhibits a strong affinity for RNA polymerase II and effectively inhibits its activity.

Smiles

CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4cc(O)ccc34)S(=O)CC(NC(=O)CNC1=O)C(=O)NC(CC(O)=O)C(=O)N1CC(O)CC1C(=O)NC(C(C)C(C)O)C(=O)N2

Molecular Formula

C39H53N9O14S

Molecular Weight

903.96

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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