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Human PD-L1 inhibitor IV

Product Specifications

CAS Number

2135542-83-3

Target

PD-1/PD-L1

Related Pathways

Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis

Bioactivity

Human PD-L1 inhibitor IV is a polypeptide compound that competitively inhibits the human PD-1 protein. It has a Kd value of 1.38 ?M and effectively blocks the interaction between hPD-1 and hPD-L1.

Smiles

CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)CN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O

Molecular Formula

C80H113N25O27

Molecular Weight

1856.932

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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