Human PD-L1 inhibitor IV
Product Specifications
CAS Number
2135542-83-3
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation|||Cell Cycle/Checkpoint|||Apoptosis
Bioactivity
Human PD-L1 inhibitor IV is a polypeptide compound that competitively inhibits the human PD-1 protein. It has a Kd value of 1.38 ?M and effectively blocks the interaction between hPD-1 and hPD-L1.
Smiles
CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)CN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O
Molecular Formula
C80H113N25O27
Molecular Weight
1856.932
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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