RIP2 Kinase Inhibitor 4
Product Specifications
CAS Number
2126803-41-4
Target
Others, PROTACs, RIP kinase
Related Pathways
NF-κB, Others, Apoptosis, PROTAC
Bioactivity
RIP2 Kinase Inhibitor 4 is a highly potent and selective RIPK2 PROTAC compound that efficiently degrades RIPK2 (pIC50 value of 8) and effectively inhibits the release of TNF-α.
Smiles
CN[C@@H](C)C(=O)N[C@H](C(=O)N1C[C@H](C[C@H]1C(=O)Nc1c(F)cccc1F)NC(=O)c1cnc(cn1)N1CCN(CCCOc2cc3ncnc(Nc4n[nH]c(C)c4C)c3cc2S(=O)(=O)C(C)(C)C)CC1)C(C)(C)C |@@:70|
Molecular Formula
C50H66F2N14O7S
Molecular Weight
1045.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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