γ-Amanitin
Product Specifications
CAS Number
21150-23-2
Target
ADC Cytotoxin, DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, Antibody-drug Conjugate/ADC Related, DNA Damage/DNA Repair
Bioactivity
γ-Amanitin, an ADC (antibody-drug conjugate) cytotoxin isolated from mushrooms, inhibits RNA polymerase II, disrupting mRNA synthesis. It exhibits effects akin to those of α-Amanitin and β-Amanitin.
Smiles
CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4cc(O)ccc34)S(=O)CC(NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)N1CC(O)CC1C(=O)NC(C(C)C(C)O)C(=O)N2
Molecular Formula
C39H54N10O13S
Molecular Weight
902.98
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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