PI3K?-IN-8
Product Specifications
CAS Number
2101518-75-4
Target
PI3K|||Others
Related Pathways
Others|||PI3K/Akt/mTOR signaling
Bioactivity
PI3K?-IN-8 is a powerful and specific oral inhibitor of PI3K?, exhibiting an IC50 of 3.3 nM. It demonstrates preferential inhibition of PI3K? when compared to PI3K?, PI3K?, and PI3K?, with IC50 values of 377.2 nM, 241.6 nM, and 17.9 nM, respectively. Furthermore, PI3K?-IN-8 possesses notable anti-tumor efficacy.
Smiles
C[C@H](Nc1nc(N)nc(N)c1C#N)c1c(-c2ccc(F)cc2)c2ccc(F)cn2c(=O)c1-c1ccccc1
Molecular Formula
C28H21F2N7O
Molecular Weight
509.521
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/59B3C5B9-2636-4321-8C89-5D555F3BB7EF/T39542
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