Aclimostat
Product Specifications
Target
Others|||Aminopeptidase
Related Pathways
Metabolism|||Others
Bioactivity
Aclimostat (ZGN-1061) is a highly potent inhibitor of the MetAP2 enzyme, demonstrating promising efficacy and safety profiles in preclinical trials. In a mouse model of obesity and insulin resistance, ZGN-1061 shows comparable weight loss efficacy to beloranib and improves metabolic parameters. Additionally, ZGN-1061 induces consistent changes in gene transcription in HepG2 cells, further supporting its positive pharmacological effects.
Smiles
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Molecular Formula
C26H42N2O6
Molecular Weight
478.63
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/497FD05E-DE71-48B4-9A1F-65B6322A86D7/T39490
CAS Number
2082752-83-6
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