Casein Kinase inhibitor A86
Product Specifications
CAS Number
2079069-01-3
Target
Others|||Casein Kinase|||Apoptosis|||CDK
Related Pathways
Stem Cells|||Cell Cycle/Checkpoint|||Metabolism|||Others|||Apoptosis
Bioactivity
Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1? (CK1?) and also inhibits CDK7 (TFIIH) and CDK9 (P-TEFb) . It induces apoptosis in leukemia cells, exhibiting substantial anti-leukemic effects.
Smiles
Cn1ncc(c1CC1CC1)-c1nc(N[C@H]2CC[C@H](N)CC2)ncc1F
Molecular Formula
C18H25FN6
Molecular Weight
344.438
Shipping Conditions
Cool pack
Storage Temperature
-20°C
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